Dr. Cormac Gahan
Dr. Cormac Gahan graduated in 1996 with a PhD in Immunology and Microbiology from University College Cork. He has since published 114 peer-reviewed articles and book chapters in journals including PNAS, Molecular Microbiology, Infection and Immunity, Vaccine and Journal of Bacteriology. His current h-index is 43 on Google Scholar (39 on ISI) with total career citations of 5766 (Google Scholar).
Dr. Gahan led the Infectious Disease programme with Prof. Colin Hill within the Alimentary Pharmabiotic Centre (www.apc.ie) from 2003-2013 and now leads the Bile Research Group within the APC with Dr. Susan Joyce. His research interests focus upon host-microbe signalling in the gut mediated via microbial bile acid metabolism (see Joyce et al., PNAS, 2014; Jones et al., PNAS, 2008 - 186 citations; Begley et al., 2005 - 445 citations). Dr. Gahan also has a long history of research work on the foodborne pathogen Listeria monocytogenes (in collaboration with Prof. Colin Hill) resulting in a number of key papers in the area (for example see Corr et al., PNAS, 2007 - 381 citations).
Recent work has also examined the use of live L. monocytogenes and L. lactis vectors as gene and protein delivery platforms for novel vaccination and therapeutic approaches. This work has been carried out in collaboration with Dr. Mark Tangney at the Cork Cancer Research Centre and Dr. Brendan Griffin in the School of Pharmacy, UCC.
In addition to his role as a funded researcher and PI in the APC he is funded by further grants from Science Foundation Ireland, the Health Research Board and the EU (FP7 and H2020).
Dr. Gahan is currently on the Editorial Board of the Journal of Pathogens and Applied and Environmental Microbiology and was on the editorial board of Journal of Applied Microbiology & Letters in Applied Microbiology from 2004-2010. He is a regular reviewer for numerous journals (including PNAS, Plos One, Microbiology, J. Bacteriol., AEM).
Dr. Gahan has given 26 invited presentations between 2008-2014 as well as numerous offered talks and posters.
Dr. Gahan directed the SFI funded UREKA summer school programme entitled Microbe-Host Interactions that provided laboratory training for 84 undergraduate students from 2006-2011.
Research interests and expertise
Bile acids as mediators of host-microbe signalling in the gut
Development of live bacterial vaccine and DNA delivery vectors
Understanding microbial pathogenesis in gut pathogens (Listeria monocytogenes & Clostridium difficile)
Culture-independent approaches to understanding the gut microbiota